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Optimizing Pharmaceutical Manufacturing Processes with EDEM particle simulation

 

Efficient handling and processing of particulates is critical to profitable manufacture of pharmaceutical products. Over 75% of all pharmaceutical products are in the solid dosage form and particulates are involved in almost every stage of the manufacturing process.

Altair EDEM software - powered by the Discrete Element Method (DEM) - accurately simulates and analyzes the behavior of granular materials such as powders, tablets and capsules. It is a powerful tool used to model common pharmaceutical manufacturing processes such as mixing, blending, granulation and tablet coating. 

This technology can provide key insights leading to optimized processes and innovation in product design.

Find out more with the resources below:

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VIDEOS - Applications Examples

 

Powder Mixing in High Shear Granulator

 

Wet Mixing Process

 

Breakage in Pin Mill

 

Die Filling 

 

Tablet Compaction

 

Tablet Mixing and Coating

 

Tablet Coating using EDEM-CFD Coupling

 

Hopper Discharge of Powders

 


 

EBOOK

Applications of EDEM for Pharmaceutical Manufacturing Processes

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Download this eBook to learn about:

  • Common challenges
  • What is EDEM simulation technology
  • Benefits of using EDEM simulation
  • Application examples: mixing, agglomeration, comminution, die filling, tablet compaction, tablet coating and more

WEBINARS

Modeling Pharmaceutical Manufacturing Processes with EDEM

On-demand

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This webinar introduces EDEM simulation technology, discusses its main applications in pharmaceutical manufacturing including mixing, coating and tableting, and shows how it can provide key information on processes otherwise difficult or sometimes impossible to measure. 

Learn how Novo Nordisk and Pfizer are using EDEM to increase process efficiency and capability, improve product quality, reduce prototyping costs, and get products to market quicker.

Webinar Contents:

• Context and Challenges
• Introducing Altair EDEM
• Applications examples: storage and conveying, mixing, milling, tableting, and tablet coating
• Q&A

WATCH RECORDING

Pharmaceutical Manufacturing Virtual Panel

On-demand

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Using the Discrete Element Method (DEM) to simulate pharmaceutical manufacturing processes

Hear insights from 4 industry experts on the use of the Discrete Element Method as a modelling tool for optimizing pharmaceutical manufacturing processes.

Topics covered:
• Challenges of understanding powder systems
• Typical DEM applications in process and product development: mixing, coating, die filling, etc.
• Regulatory framework: using models for regulatory purposes
• Digital design / digital twin
• How DEM can help fast and efficient drug development and manufacturing in the current context

WATCH RECORDING

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